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Sudden Death From Ruptured Choroid Plexus Arteriovenous Malformation

Cioca, Andreea MD*†; Gheban, Dan MD, PhD*‡; Perju-Dumbrava, Dan MD, PhD; Chiroban, Ovidiu MD; Mera, Mihaela MD, PhD*†

The American Journal of Forensic Medicine and Pathology: June 2014 - Volume 35 - Issue 2 - p 100–102
doi: 10.1097/PAF.0000000000000091
Case Reports

Brain vascular malformations are recognized as having potential to produce hemorrhage, but leading to sudden death in children is uncommon. Arteriovenous malformations may be situated in any region of the brain, but very rarely, they can be restricted to the choroid plexus. We report here a rare case of sudden death in a child, caused by a ruptured vascular malformation with an unusual location, which was not identified grossly but only on histological examination. The size and the location of the lesion, as well as the age of our patient, were contributing factors of the massive bleeding. Autopsy remains an important tool because it provides valuable information about the etiology of such bleedings, improves knowledge about these lesions, and enhances epidemiologic data.

From the *“Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania; †Department of Pathology, County Emergency Hospital, Cluj-Napoca, Romania; ‡Department of Pathology, Children’s Emergency Hospital, Cluj-Napoca, Romania; and §Department of Legal Medicine, Institute of Legal Medicine, Cluj-Napoca, Romania.

Manuscript received November 22, 2013; accepted January 9, 2014.

The authors report no conflicts of interest.

Reprints: Andreea Cioca, MD, “Iuliu Hatieganu” University of Medicine and Pharmacy, Street Victor Babes, no. 8, 400012, Cluj-Napoca, Romania. E-mail:

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© 2014 by Lippincott Williams & Wilkins.