Institutional members access full text with Ovid®

Share this article on:

Inverted Takotsubo Cardiomyopathy—Clinicopathologic Correlation

Tran, Khoa MBBS, FRACP, FCICM*; Milne, Nathan MBBS, FRCPA; Duhig, Edwina MBBS, FRCPA; Altman, Mikhail MD, FRACP§

The American Journal of Forensic Medicine and Pathology: September 2013 - Volume 34 - Issue 3 - p 217–221
doi: 10.1097/PAF.0b013e31829f653e
Case Reports

We report the case of a 34-year-old woman who presented after a witnessed out-of-hospital arrest. Initial cardiac rhythm at the time of resuscitation was ventricular fibrillation. Subsequently in hospital, she developed further episodes of polymorphic ventricular tachycardia and ventricular fibrillation. Urgent echocardiography showed features suggestive of an inverted takotsubo cardiomyopathy. Twenty-four hours after admission, there was a further episode of polymorphic ventricular tachycardia from which the patient could not be resuscitated. An autopsy confirmed the cause of death as inverted takotsubo cardiomyopathy. We present the pathological findings from the postmortem autopsy.

Supplemental Digital Content is available in the article.

From the *Intensive Care Unit, Logan Hospital, Meadowbrook; †Forensic Pathology, Coopers Plains; ‡Department of Anatomical Pathology, The Prince Charles Hospital, Chermside; and §Department of Cardiology, Logan Hospital, Meadowbrook, Queensland, Australia.

Manuscript received January 6, 2013; accepted April 21, 2013.

No funding was received for this study.

The authors report no conflicts of interest.

Reprints: Khoa Tran, MBBS, FRACP, FCICM, Intensive Care Unit, Logan Hospital, Corner Armstrong and Loganlea Rds, Meadowbrook, Queensland 4131, Australia. E-mail:

Supplemental digital contents are available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s Web site (

© 2013 by Lippincott Williams & Wilkins.