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Death Due to Eosinophilic Necrotizing Myocarditis Despite Steroid Treatment

Huston, Butch MD; Froloff, Victor MD; Mills, Kelly MD; McGee, Michael MD

The American Journal of Forensic Medicine and Pathology: June 2013 - Volume 34 - Issue 2 - p 95–97
doi: 10.1097/PAF.0b013e3182887818
Case Reports

We report a case of a 16-year-old boy who was treated for a suspected dental infection with a tooth extraction and amoxicillin therapy. The decedent developed a rash and presented to the emergency department with what was thought to be a possible allergic reaction to amoxicillin despite completion of the antibiotic course. The patient was given a course of prednisone. Several weeks later, while still completing the course of prednisone, the patient experienced shortness of breath and collapsed. Resuscitation efforts were unsuccessful. Postmortem examination revealed a necrotizing eosinophilic myocarditis. This case reveals that despite steroid therapy, a patient may still die of eosinophilic myocarditis.

From the Ramsey County Medical Examiner’s Office, St Paul, MN.

Manuscript received January 12, 2012; accepted December 5, 2012.

The authors report no conflicts of interest.

Reprints: Butch Huston, MD, Ramsey County Medical Examiner’s Office, 300 E. University Ave. St Paul, MN 55101. E-mail:

© 2013 Lippincott Williams & Wilkins, Inc.