Original Article: PDF OnlyCornoid lamellation A histologic reaction patternWade, Thomas R. M.D.; Ackerman, A. Bernard M.D. Author Information From the Departments of Dermatology and Pathology, New York University School of Medicine, New York, New York. The American Journal of Dermatopathology 2(1):p 5-16, Spring 1980. Buy Abstract Cornoid lamellation is a constant histologic marker of porokeratosis in its many variants. This histologic appearance, heretofore thought to be pathognomonic of and restricted to porokeratosis alone, has also been found by us in a variety of other conditions. Cornoid lamellation is, therfore, analogous to the histologic findings of focal acantholytic dyskeratosis, epidermolytic hyperkeratosis, and follicular mucinosis as a distinctive histologic reaction pattern that reflects disordered progression of epidermal cells to cornification. © Lippincott-Raven Publishers.