Extraordinary Case ReportLymphomatoid Papulosis With a Unique T Follicular Helper–Like PhenotypeTran, Jessica BBA*; Duvic, Madeleine MD*; Torres-Cabala, Carlos A. MD†Author Information *Department of Dermatology, The University of Texas MD Anderson Cancer Center, Houston, TX and †Department of Pathology, Dermatopathology Section, The University of Texas MD Anderson Cancer Center, Houston, TX. Correspondence: Jessica Tran, BBA, 3400 Montrose Blvd, Houston, TX 77006 (e-mail: [email protected]). The authors declare no conflicts of interest. The American Journal of Dermatopathology: October 2020 - Volume 42 - Issue 10 - p 776-779 doi: 10.1097/DAD.0000000000001693 Buy Metrics Abstract Lymphomatoid papulosis (LyP) is a benign skin condition that typically presents with grouped or scattered lesions on the body that self-resolve within weeks or months of onset. LyP belongs to the group of CD30-positive lymphoproliferative disorders. Several histological variants of LyP exist, and the histological features of LyP can overlap with other lymphoproliferative disorders; therefore, both histological and clinical correlations are needed for a proper diagnosis of LyP. We report an unusual case of LyP displaying a T follicular helper cell–like phenotype and histopathologically resembling the primary cutaneous CD4-positive small-sized to medium-sized T-cell lymphoproliferative disorder. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.