Extraordinary Case ReportApocrine ChromhidrosisShah, Aadarsh MRCP, MBBS, BSc*; Tsianou, Zoi MRCP, MD†; Suchak, Ravi MRCP, MBBS†; Mann, Jack MRCP, MBBS, BSc†Author Information *St John's Institute of Dermatology, Guy's and St Thomas' Hospital, Great Maze Pond, London, United Kingdom; and †Dermatology Department, Basildon and Thurrock University Hospital, Basildon, Essex, United Kingdom. Correspondence: Aadarsh Shah, MRCP, MBBS, BSc, St John's Institute of Dermatology, Guy's and St Thomas' Hospital, Great Maze Pond, London SE1 9RT, United Kingdom (e-mail: [email protected]). The authors declare no conflicts of interest. The American Journal of Dermatopathology: October 2020 - Volume 42 - Issue 10 - p e147-e148 doi: 10.1097/DAD.0000000000001712 Buy Metrics Abstract Apocrine chromhidrosis is a rare diagnosis that occurs due to colored sweat being secreted from the apocrine glands, which are located in the axillae, anogenital skin, and areolae and over the skin of the trunk, face, and scalp. We present the case of a 65-year-old woman who presented with a sudden onset of pink sweating affecting mainly her axillae but also her pelvis, causing staining of clothing and bed sheets. There was nil to note on examination and histology with immunostaining demonstrated focally prominent yellow-brown lipofuscin granules in the cytoplasm of the apocrine secretory cells confirming the diagnosis. The disease can have a significant psychosocial impact, and treatment remains challenging. Our case is unique because the red and pink coloring of sweat is less common in cases of apocrine chromhidrosis, which is often in favor of darker colored sweat, and the distribution involved the inguinal canal, which is also less often seen. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.