Extraordinary Case ReportEpstein–Barr Virus-Positive Mucocutaneous Ulcer in a Pediatric Patient—Case ReportCoelho, Karina Munhoz de Paula Alves MSc*,†; Bublitz, Giuliano Stefanello MSc*; Condeixa de França, Paulo Henrique PhD†; Stall, Jaqueline BSc*,†; Hanauer, Aline Denise MSc†,‡; Sangueza, Júlio Martín MD§Author Information *Dermatopathology Department, Centro de Diagnósticos Anátomo-Patológicos—CEDAP, Joinville, Brazil; †Post-Graduate Program in Health and Environment Department, Universidade da Região de Joinville—UNIVILLE, Joinville, Brazil; ‡Pediatric Surgery Department, Hospital Infantil Dr. Jeser Amarante Farias, Joinville, Brazil; and §Department of Dermatopathology, Obrero Hospital, La Paz, Bolivia. Correspondence: Karina Munhoz de Paula Alves Coelho, Centro de Diagnósticos Anátomo-Patológicos—CEDAP, Mario Lobo Street, 61, 89201-330 Joinville, Santa Catarina, Brazil (e-mail: firstname.lastname@example.org). The authors declare no conflicts of interest. Online date: April 18, 2020 The American Journal of Dermatopathology: April 2020 - Volume 42 - Issue 4 - p e49-e52 doi: 10.1097/DAD.0000000000001568 Buy Metrics Abstract The Epstein–Barr virus (EBV)-positive mucocutaneous ulcer is a rare entity in the spectrum of lymphoproliferative diseases associated with the EBV. It occurs typically in patients with immunosuppression associated with immunosenescence, as well as due to iatrogenic causes, posttransplant patients and primary immunodeficiency disorders. It is often a benign and self-limited disease that recedes by stopping or reducing the immunosuppressive agents in most of the cases. Histologically, it is characterized by a population of EBV-positive atypical lymphoid cells. Here, we present a rare case of a 5-month-old pediatric patient, born preterm at 24 weeks of gestational age, presenting a lump on the right shoulder, later evolving to EBV-positive mucocutaneous ulcer. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.