Extraordinary Case ReportCutaneous Metastasis of Choriocarcinoma in 2 Male Patients: A Rare Presentation of an Aggressive Malignancy That Dermatopathologists Must RecognizeMarka, Arthur BS*; Hoyt, Brian S. MD†; LeBlanc, Robert E. MD*,‡Author Information *Dartmouth Geisel School of Medicine, Hanover, NH; †Section of Dermatology, Dartmouth-Hitchcock Medical Center, Lebanon, NH; and ‡Department of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH. Correspondence: Robert E. LeBlanc, MD, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756 (e-mail: [email protected]). The authors declare no conflicts of interest. The American Journal of Dermatopathology: January 2019 - Volume 41 - Issue 1 - p 50-54 doi: 10.1097/DAD.0000000000001209 Buy Metrics Abstract Testicular choriocarcinoma needs to be considered in the differential diagnosis of cutaneous metastases in young adult men because of its propensity for early hematogenous dissemination. Furthermore, the diagnosis may not be suspected in many cases in which there is clinically no testicular enlargement. This highly aggressive germ cell tumor typically metastasizes to the liver, lungs, and brain. Skin metastasis is exceedingly rare with only 22 cases previously reported in the world literature. We herein report 2 additional cases: a 25-year-old man and a 32-year-old man, both of whom were treated for mixed germ cell tumors and developed multiple cutaneous metastases to the head. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.