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Induction of Desmoplastic Trichoepithelioma in a Dermatofibroma

Georgescu, Mihaela, MD*; Blödorn-Schlicht, Norbert, MD; Böer-Auer, Almut, MD

The American Journal of Dermatopathology: December 2018 - Volume 40 - Issue 12 - p 924–926
doi: 10.1097/DAD.0000000000000982
Extraordinary Case Report
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Abstract: Induction of follicular germinative structures above a dermatofibroma (DF) is a common finding. Rarely, induction of a trichoblastoma in a DF has been observed. Here, we report the case of a desmoplastic trichoepithelioma induced by a DF. The lesion with clinical and histological appearance of a DF situated on the left dorsal foot showed an associated adnexal proliferation that fulfilled histopathological criteria of desmoplastic trichoepithelioma. Immunohistochemistry (Ber-EP4, Bcl-2, CK17, CK20, CK7, EMA, and Ki67) helped to confirm the diagnosis and to exclude possible differential diagnoses.

*Dermatology Department, “Dr. Carol Davila” Central Military Emergency University Hospital, Bucharest, Romania; and

Dermatopathology Laboratory, Dermatologikum, Hamburg, Germany.

Correspondence: Almut Böer-Auer, MD, Dermatopathology Laboratory, Dermatologikum, 20354 Hamburg, Germany (e-mail: boer@dermatologikum.de).

The authors declare no conflicts of interest.

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