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Cutis Laxa Acquisita After Urticarial Vasculitis in SLE Patients

Golisch, Kimberly B., BS*; Gottesman, Silvija P., MD; Ferrer, Patricia, PA-C; Culpepper, Keliegh S., MD§

The American Journal of Dermatopathology: June 2018 - Volume 40 - Issue 6 - p 433–437
doi: 10.1097/DAD.0000000000001084
Extraordinary Case Report

Abstract: Cutis laxa is a rare connective tissue disease involving damage to dermal elastic fibers creating a clinical appearance of loose, sagging skin. The condition can be either acquired or genetic. Autoimmune diseases, neoplasms, infections, and medications have been proposed as the cause of, or in association with, the acquired form. In nearly 50% of cases, erythematous plaques present before the onset of cutis laxa. Separately, urticarial vasculitis and systemic lupus erythematosus have been linked to cutis laxa acquisita. Our case is the first in the literature documenting a coexistence of cutis laxa acquisita, hypocomplementemic urticarial vasculitis, and systemic lupus erythematosus.

*University of Arizona College of Medicine, Tucson, AZ;

Ackerman Academy of Dermatopathology, New York, NY;

Dyson Dermatology, Tucson, AZ; and

§Division of Dermatopathology, Department of Medicine, University of Arizona, Tucson, AZ.

Correspondence: Kimberly B. Golisch, BS, University of Arizona College of Medicine, 1501 N Campbell Avenue, Tucson, AZ 85724 (e-mail:

The authors declare no conflicts of interest.

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