CME ArticlePigmented Deposits in the SkinFernandez-Flores, Angel MD, PhD*,†,‡; Bermúdez, Carmen Fachal MD§; Molina, Inmaculada MD¶; Saus, Carles MD, PhD‖; Monteagudo, Carlos MD, PhD**,††,‡‡; Cassarino, David Cassarino MD, PhD§§Author Information *Consultant Histopathologist, Department of Cellular Pathology, Hospital El Bierzo, Ponferrada, Spain; †Associate Researcher, Biomedical Investigation Institute of A Coruña, CellCOM-SB Group, A Coruña, Spain; ‡Consultant Histopathologist, Department of Cellular Pathology, Hospital de la Reina, Ponferrada, Spain; §Consultant Histopathologist, Department of Pathology, Hospital Alvaro Cunqueiro (EOXI), Vigo, Spain; ¶Consultant Dermatologist, Department of Dermatology, Hospital Clinico Universitario de Valencia, Valencia, Spain; ‖Consultant Histopathologist, Department of Pathology, Hospital Universitario Son Espases, Palma, Spain; **Biomedical Research Institute INCLIVA, Valencia, Spain; ††Professor, Department of Anatomic Pathology, University of Valencia, Medical School, Valencia, Spain; ‡‡Chief, Dermatopathology Section, Department of Anatomic Pathology, Hospital Clinico Universitario de Valencia, Valencia, Spain; and §§Consultant Dermatopathologist, Department of Pathology, Sunset Medical Center, Southern California Permanente Medical Group, Los Angeles, CA. Correspondence: Angel Fernandez-Flores, MD, PhD, Servicio de Anatomía Patologica, Hospital El Bierzo, Medicos sin Fronteras 7, 24411, Ponferrada, Spain (e-mail: [email protected]). All authors and staff in a position to control the content of this CME activity and their spouses/life partners (if any) have disclosed that they have no financial relationships with, or financial interests in, any commercial organizations pertaining to this educational activity. The American Journal of Dermatopathology: May 2018 - Volume 40 - Issue 5 - p 307-328 doi: 10.1097/DAD.0000000000000944 Buy Metrics Abstract Pigmented deposits can occur in the skin due to many and varied causes. Some of them are systemic conditions accompanied by involvement of internal organs. Others have serious prognostic implications, and early diagnosis can help in the correct and adequate management of the diseases. In addition, some of them are quite innocuous and the correct diagnosis avoids unnecessary treatments. In this article, we review the morphologic features of some of the most common and some of the less usual pigmented deposits in skin other than tattoos. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.