Secondary Logo

Journal Logo

Institutional members access full text with Ovid®

Perineurial Vascular Hamartoma

Ronen, Shira MD*; Klaassen, Rodrigo MD; Suster, Saul MD*

The American Journal of Dermatopathology: April 2018 - Volume 40 - Issue 4 - p 275–278
doi: 10.1097/DAD.0000000000000981
Extraordinary Case Report

Abstract: Perineural vascular proliferations are extremely rare, and only a few cases have been reported in the literature, usually under the designation of “intraneural hemangioma.” We report a case of a 28-year-old man with a nodule in the right palm of his hand that developed over an 8- to- 12-month period. Microscopic examination revealed a vascular proliferation growing within connective tissue and entrapping small nerve bundles. The features of the lesion are consistent with an unusual hamartomatous growth of small vessels and nerves rather than a hemangioma arising within a nerve. Clinical and histological details, and a discussion of the relevant literature on this unusual lesion, are provided.

*Department of Pathology, Medical College of Wisconsin, Milwaukee, WI; and

Department of Pathology, University of Concepcion, Concepcion, Chile.

Correspondence: Saul Suster, MD, Department of Pathology, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226 (e-mail:

The authors declare no conflicts of interest.

Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.