Although the normal histology of anogenital mammary-like glands (AGMLG) has been studied, no systemic investigation has been performed on the immunoprofile of these structures. We studied intact AGMLG with a broad panel of antibodies. The immunoprofile of AGMLG is similar to that of a normal breast tissue, and there are similarities to eccrine glands and coils about cytokeratin expression. Our immunohistochemical data may contribute to understanding of the pathogenesis of lesions arising from AGMLG.
*Department of Pathology, Clinical Research and Practical Center for Specialized Oncological Care, Saint-Petersburg, Russia;
†Department of Pathology, Medical Faculty, Saint-Petersburg State University, Saint-Petersburg, Russia;
‡Department of Pathology, Saint-Petersburg Medico-Social Institute, Saint-Petersburg, Russia;
§Department of Histopathology, King Edward Memorial Hospital, Perth, Australia;
¶Sikl's Department of Pathology, Medical Faculty in Pilsen, Charles University in Prague, Pilsen, Czech Republic;
‖Department of Dermatology, Medical Military Academy, Saint-Petersburg, Russia; and
**Bioptical Laboratory, Pilsen, Czech Republic.
Reprints: Dmitry V. Kazakov, MD, PhD, Sikl's Department of Pathology, Charles University Medical Faculty Hospital, Alej Svobody 80, 304 60 Pilsen, Czech Republic (e-mail: firstname.lastname@example.org).
Supported in part by the Charles University Research Fund (project number SVV-2016–260 282).
The authors declare no conflicts of interest.