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Morphological Findings of Deep Cutaneous Fungal Infections

Fernandez-Flores, Angel MD, PhD*; Saeb-Lima, Marcela MD; Arenas-Guzman, Roberto MD

The American Journal of Dermatopathology: July 2014 - Volume 36 - Issue 7 - p 531–556
doi: 10.1097/DAD.0b013e31829cc6f3
CME Article

Abstract: Cutaneous fungal infections used to be rare in most developed countries. However, they have become more common due to immunosuppression and globalization. In this report, we summarize the histopathologic findings of the main cutaneous fungal infections that are commonly seen in daily practice, including eumycetoma, sporotrichosis, histoplasmosis, cryptococcosis, coccidioidomycosis, aspergillosis, zygomycosis, phaeohyphomycosis, alternariosis, blastomycosis, paracoccidioidomycosis, lobomycosis, and chromoblastomycosis. We also include protothecosis (despite the fact that the infectious agent of this disease is algal and not fungal) and rhinosporidiosis (despite being caused by mesomycetozoea, which are not fungi).

*Consultant Histopathologist, Dermatopathology and Lymphoid Area, Department of Cellular Pathology, Hospital El Bierzo, Ponferrada, Spain;

Dermatologist, Department of Pathology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, INER/CIENI, Hospital Angeles Lomas, Centro Medico ABC, Huixquilucan, México; and

Dermatologist and Mycologist, Hospital General Dr. Manuel Gea Gonzalez, Mexico City, México.

Reprints: Angel Fernandez-Flores, MD, PhD, Servicio de Anatomía Patologica, Hospital El Bierzo, Medicos sin Frontreas 7, 24411 Ponferrada, Spain (e-mail:

All authors and staff in a position to control the content of this CME activity and their spouses/life partners (if any) have disclosed that they have no financial relationships with, or financial interests in, any commercial organizations pertaining to this educational activity.

© 2014 by Lippincott Williams & Wilkins.