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Cavernous Hemangioma–Like Kaposi Sarcoma: A Unique Histopathologic Variant

Sutton, Angela M. DO*; Tarbox, Michelle MD; Burkemper, Nicole M. MD

The American Journal of Dermatopathology: May 2014 - Volume 36 - Issue 5 - p 440–442
doi: 10.1097/DAD.0b013e3182974502
Extraordinary Case Report

Abstract: Kaposi sarcoma (KS) is an angiolymphatic neoplasm with multifactorial etiology. Clinically, KS has been divided into 4 distinct types and 3 well-defined histologic stages. Rare reports in the literature have characterized additional unique histopathologic variants. The authors report a case of KS, confirmed with human herpesvirus type 8 and D2-40 staining, which resembled a cavernous hemangioma on histopathology.

*Department of Internal Medicine, Riverside Methodist Hospital, Columbus, OH;

Department of Dermatology, Texas Tech University Health Sciences Center, Lubbock, TX; and

Department of Dermatology, Saint Louis University, St. Louis, MO.

Reprints: Nicole M. Burkemper, MD, 1755 South Grand Boulevard, St. Louis, MO 63104 (e-mail:

The authors declare no conflicts of interest.

© 2014 by Lippincott Williams & Wilkins.