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Syringocystadenocarcinoma Papilliferum In Situ: Report of a Case With Late Recurrence

Castillo, Laura MD; Moreno, Amalia MD; Tardío, Juan C. MD, PhD

The American Journal of Dermatopathology: April 2014 - Volume 36 - Issue 4 - p 348–352
doi: 10.1097/DAD.0b013e3182a38bb9
Extraordinary Case Report

Abstract: Syringocystadenocarcinoma papilliferum (SCACP) is an extremely rare cutaneous neoplasm with apocrine differentiation. Only 27 cases have been reported up-to-date, 8 of them described as carcinomas in situ. Two cases with local recurrence and 3 cases with regional lymph node metastases have been documented. The authors present the case of a 32-year-old female with a SCACP in situ on the scalp that recurred 8 years after the excision of the primary tumor. No SCACP with late recurrence have been previously reported. This case highlights the need for a long-term follow-up in patients with this type of carcinoma.

Department of Pathology, Hospital Universitario de Fuenlabrada, Fuenlabrada, Madrid, Spain.

Reprints: Juan C. Tardío, MD, PhD, Servicio de Anatomía Patológica, Hospital Universitario de Fuenlabrada, Camino del Molino 2, 28942 Fuenlabrada, Madrid, Spain (e-mail:

The authors declare no conflict of interest and source of funding.

© 2014 by Lippincott Williams & Wilkins.