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Widespread Atypical Vascular Lesions of the Skin After Whole-Body Electron Beam Therapy

Expanding the Clinical Spectrum

Sinclair, Werner, MBChB, MMed (Dermatol)

The American Journal of Dermatopathology: February 2013 - Volume 35 - Issue 1 - p e11–e15
doi: 10.1097/DAD.0b013e318268175c
Extraordinary Case Report
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Abstract: Atypical vascular lesion of the skin is an uncommon usually benign condition, thus far reported almost exclusively from mammary skin after radiotherapy for carcinoma of the breast. Some clinical and histological overlap exists with early angiosarcoma, which can also occur on irradiated skin. The lesions are divided into vascular and lymphatic types, the first representing a higher risk for development of angiosarcoma and the latter being more common. This article reports a rare case of widespread, progressive, vascular-type atypical vascular lesion after repeated whole-body electron beam irradiation administered as treatment for mycosis fungoides.

Department of Dermatology, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.

Reprints: Werner Sinclair, MBChB, MMed (Derm), Department of Dermatology, Faculty of Health Sciences, University of the Free State, PO Box 339 (M7), Bloemfontein 9300, South Africa (e-mail: sinclairw@ufs.ac.za).

The author declares no conflicts of interest.

© 2013 by Lippincott Williams & Wilkins.