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Nonpigmented Intradermal Malignant Melanoma With Cribiform, Myxoid, and Spindle Cell Growth Patterns

Harmse, Dean MBChB, FRCPath; Saunders, Sarah BSc(Hons), MBChB; Evans, Alan MBChB, FRCPath

The American Journal of Dermatopathology: December 2010 - Volume 32 - Issue 8 - p 829-831
doi: 10.1097/DAD.0b013e3181d564cb
Extraordinary Case Report

We describe an unusual variant of intradermal malignant melanoma without any junctional component. The lesion differed from other intradermal melanomas in that it was devoid of pigmentation and was composed of mainly spindle-shaped cells. Within the lesion, there were areas of pseudoglandular and myxoid changes resembling the rare myxoid melanoma. In addition to this, there were areas with an alveolar-like architecture containing nested groups of cells.

From the East Midlands Forensic Pathology Unit, Leicestershire United Kingdom.

Reprints: Sarah Saunders, BSc(Hons), MBChb, Level 3, Robert Kilpatrick Clinical Sciences Building, Leicester Royal Infirmary, Leicester, Leicestershire LE2 7LX, United Kingdom (e-mail:

© 2010 Lippincott Williams & Wilkins, Inc.