Extraordinary Case ReportCutaneous Metastasis of Uterine Papillary Serous CarcinomaKim, Eun Sung MD; Lee, Deuk Pyo MD; Lee, Mi Woo MD; Choi, Jee Ho MD; Moon, Kee Chan MD; Koh, Jai Kyoung MDAuthor Information From the Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. Reprints: Mi Woo Lee, Department of Dermatology, Asan Medical Center, University of Ulsan, College of Medicine, 388-1 Poongnap-dong, Songpa-gu, Seoul, 138-736 Korea (e-mail: [email protected]). The American Journal of Dermatopathology: October 2005 - Volume 27 - Issue 5 - p 436-438 doi: 10.1097/01.dad.0000178002.19337.b1 Buy SDC Metrics Abstract Uterine papillary serous carcinoma (UPSC) is an uncommon highly malignant variant of endometrial adenocarcinoma that histologically and clinically resembles papillary serous carcinoma of the ovary. This case demonstrates a very rare case of cutaneous metastasis of uterine papillary serous carcinoma. A 54-year-old Korean female developed multiple pruritic skin nodules on the pubic area 13 months later after diagnosis of uterine papillary serous carcinoma. A biopsy of the skin lesions showed papillary serous carcinoma, compatible with her primary tumor. Without clinical history, it is difficult to distinguish other types of metastatic carcinoma to the skin and primary apocrine carcinoma of the skin from metastatic uterine papillary serous carcinoma. Whereas uterine papillary serous carcinoma only rarely involves the skin, this entity should be included in the differential diagnosis of papillary adenocarcinoma in the skin. © 2005 Lippincott Williams & Wilkins, Inc.