Secondary Syphilis: PDF OnlyA Clinicopathological StudyJordaan, H. Francois M.D.Author Information From the Department of Dermatology. Tygerberg Hospital, Tygerberg, Republic of South Africa. Consultant. The American Journal of Dermatopathology: October 1988 - Volume 10 - Issue 5 - p 399-409 Buy Abstract Syphilis is still a common disease in many countries. The clinical features of secondary syphilis are well documented, and the histopathological features of secondary syphilis have been reviewed in a few studies. The present study documents the histopathology of secondary syphilis based on 68 skin biopsies from 38 patients. Based on the findings of this study, and a review of the literature, diagnostic guidelines are suggested and the differential diagnoses are discussed. © Lippincott-Raven Publishers.