NINE PATIENTS WITH METASTATIC SEMINOMA Who had received no prior chemotherapy were induced with a combination containing cis-platinum 120mg m21 V and cyclophamide 600mg/m21 V treatments at 4–6 weeks intervals, and then received maintenance with cyclophosphamide 600 mg,/m2 1.V. every 3–4 weeks to complete 2 years of chemotherapy. Eight patients entered complete remission: five with chemotherapy alone and three with chemotherapy and radiation or resection of residual disease. Seven patients remain in CR with a minimum follow up of 17 months. Chemotherapy is effective in treatment of metastatie seminoma.
Memorial Sloan-Kettering Cancer Center, New York, New York.
a Solid Tumor Service, Department of Medicine.
b Urology Service Department of Surgery.
c Radiation Therapy Department.