Therapeutic OpinionPrecision Surgery for ObesityDong, Zhiyong MD1; Shariful Islam, Sheikh Mohammed PhD2,3,4; Simms-Walker, Enan BS4; Wang, Cunchuan PhD1,*Author Information 1Department of Bariatric Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China; 2Cardiovascular Division, The George Institute for Global Health, Camperdown, New South Wales, Australia; 3Faculty of Health, School of Exercise and Nutrition Sciences, Institute of Physical Activity and Nutrition (IPAN), Deakin University, Melbourne, Victoria, Australia; and 4Sydney Medical School, The University of Sydney, Camperdown, New South Wales, Australia. *Address for correspondence: Department of Bariatric Surgery, The First Affiliated Hospital of Jinan University, No. 613 Huangpu Avenue West, Guangzhou 510630, China. E-mail: [email protected]. The authors have no conflicts of interest to declare. Z. Dong and S. M. Shariful Islam have contributed equally. American Journal of Therapeutics: September/October 2020 - Volume 27 - Issue 5 - p e491-e494 doi: 10.1097/MJT.0000000000000783 Buy Metrics Abstract Precision medicine is targeted towards improving the effectiveness of treatment, reducing the side effects of drugs and reducing medical costs. The application of precision surgery for obesity is a new concept that involves 2 stages: the first stage is to attain a precise obesity surgery, and the second stage is to achieve individualized obese gene therapy. In this article, we discuss the value of precision surgery for obesity, its stages and its future application to improve obesity surgery. Due to recent advancements in medical technologies, genetics, surgical and clinical research; precision surgery for obesity will lead the future of obesity surgery. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.