Intravenous Immunoglobulin and Methylprednisolone for Clozapine-Associated PerimyocarditisCheng, Albert MD; Ahmed, Mohanned MD; Shuaib, Waqas MD*American Journal of Therapeutics: July/August 2019 - Volume 26 - Issue 4 - p e485–e486 doi: 10.1097/MJT.0000000000000751 Therapeutic Challenges Buy Abstract Author InformationAuthors Article MetricsMetrics Clinical Features: Cardiotoxicity is a rare but serious side effect of clozapine. We present a case of a psychiatric patient on chronic clozapine 75 mg daily, who presented with congestive heart failure secondary to the cardiotoxic effects of the psychiatric medication. Therapeutic Challenge: Conventional heart failure treatment failed to improve symptoms. Solution: A course of 40 mg of intravenous immunoglobulin and 125 mg of steroids was implemented, after which the patient made a full recovery. We hope to raise awareness of concurrent clozapine-induced pericarditis and myocarditis and propose a role of intravenous immunoglobulin and steroids in the treatment of drug-induced cardiomyopathy. Wichita Falls Family Practice Residency Program, Wichita Falls, TX. Address for correspondence: Wichita Falls Family Practice Residency Program, 1301 3rd St, Suite 200, Wichita Falls, TX 76301. E-mail: Waqas1184@hotmail.com The authors have no conflicts of interest to declare. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.