Case ReportsLindane Neurotoxicity in ChildhoodSingal, Anjum; Thami, Gurvinder P.* Author Information Department of Dermatology and Venereology, Government Medical College Hospital, Chandigarh, India *Address for correspondence: Department of Dermatology and Venereology, Government Medical College Hospital, Sector 32 B, Chandigarh, 160030 India. E-mail: [email protected] American Journal of Therapeutics 13(3):p 277-280, May 2006. | DOI: 10.1097/01.mjt.0000212707.81034.c6 Buy Metrics Abstract Lindane (gamma-benzene-hexachloride) has been widely used as an antiscabetic and a pediculicidal agent for the past 50 years with reasonably good efficacy. After its initial use as a first-line therapy, there have been several reports of its neurotoxicity, especially among infants and young children. Literature review reveals that the risk of its neurotoxicity is minimal if used properly and strictly according to the prescribed recommendations. However, following availability of other safer and equally efficacious alternatives, it is now being regarded as a second-line therapy for scabies and pediculosis. © 2006 Lippincott Williams & Wilkins, Inc.