Secondary Logo

Journal Logo

Institutional members access full text with Ovid®

Age-related Hearing Loss and Dementia

Chern, Alexander MD; Golub, Justin S. MD, MS

Alzheimer Disease & Associated Disorders: July–September 2019 - Volume 33 - Issue 3 - p 285–290
doi: 10.1097/WAD.0000000000000325
Review Article
Buy

Dementia is a devastating disease and global health challenge that is highly prevalent worldwide. A growing body of research has shown an independent association between age-related hearing loss (ARHL) and dementia, identifying ARHL as a compelling potential target in preventive strategies for dementia. However, a causal linkage between ARHL and dementia needs to be investigated before making definitive clinical guidelines and treatment recommendations regarding ARHL as a modifiable risk factor. In this review, we discuss the association between ARHL and dementia, the importance of addressing this finding, as well as common mechanisms (eg, microvascular disease) and causal mechanisms (eg, depletion of cognitive reserve and social isolation) that may explain the nature of this relationship. Future directions for research are also highlighted, including randomized controlled trials, developing high-resolution microvascular imaging, and further refining audiometric testing.

Department of Otolaryngology-Head & Neck Surgery, Columbia University Irving Medical Center, New York, NY

The authors declare no conflicts of interest.

Reprints: Alexander Chern, MD, Department of Otolaryngology-Head & Neck Surgery, Columbia University Irving Medical Center, 180 Fort Washington Avenue, Harkness Pavilion, Room 865, New York, NY 10032 (e-mail: alc9230@nyp.org).

Received December 19, 2018

Accepted May 10, 2019

Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved