*Departments of Psychiatry
‡Neurology
§Epidemiology, University of California, San Francisco (UCSF)
†Mental Health Research Service, The San Francisco Veterans Affairs Medical Center, San Francisco
¶Department of Neurology, University of California, Davis
∥Departments of Neuroscience and Public Health, University of Calfornia, Berkeley, CA
Dr Barnes is supported by a Career Development Award from the National Institute on Aging (K01 AG024069). Posit Science Corporation installed and removed the computers used for this study, trained subjects to use the computers, and provided research support to Drs Barnes, Jagust, Reed, and Kramer. Dr Belfor was a postdoctoral fellow in the Department of Psychiatry at UCSF and was employed in the department at the time this study was performed and was later employed briefly by Posit Science Corporation after the study was completed. Drs Yaffe and DeCarli have nothing to disclose.
Reprints: Deborah E. Barnes, PhD, MPH, University of California, 4150 Clement Street (151R), San Francisco, CA 94121 (e-mail: [email protected]).
Received for publication January 29, 2008
accepted October 22, 2008
The results of this study were presented at the American Academy of Neurology meeting in San Diego, CA, on April 5, 2006, and at the International Conference on Alzheimer's Disease in Madrid, Spain, on July 18, 2006.
Final decisions about study design, data collection, analysis and interpretation, and manuscript content were made by the authors independent of Posit Science. The authors had full access to all the data, the right to publish all the data, and performed all statistical analyses reported in this manuscript. Dr Barnes takes responsibility for the integrity of the data and the accuracy of the data analysis. This trial is registered at ClinicalTrials.gov (NCT00319943).