Original ArticlesThe Spanish Translation and Adaptation of the Uniform Data Set of the National Institute on Aging Alzheimer's Disease CentersAcevedo, Amarilis PhD*; Krueger, Kristin R. PhD†; Navarro, Ellen MA‡; Ortiz, Freddy PhD§; Manly, Jennifer J. PhD∥; Padilla-Vélez, Margarita M. PhD∥; Weintraub, Sandra PhD‡; López, Oscar L. MD¶; Mungas, Dan PhD♯Author Information *Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL †Department of Behavioral Sciences, Alzheimer's Disease Center, Rush University Medical Center ‡Cognitive Neurology and Alzheimer's Disease Center, Northwestern University, Chicago, IL §Department of Neurology, Alzheimer Disease Research Center, David Geffen School of Medicine at UCLA, University of California, Los Angeles ♯Department of Neurology, University of California, Davis, CA ∥Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY ¶Department of Neurology & Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA Supported by NACC UO1 AG016976 from the National Institute on Aging to Walter A. Kukull, PhD, Principal Investigator. Reprints: Amarilis Acevedo, PhD, Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, MRI Building, 2nd Floor, 4300 Alton Road, Miami Beach, FL 33140 (e-mail: firstname.lastname@example.org). Received for publication May 9, 2008; accepted October 14, 2008 In addition to the contribution of coauthor Sandra Weintraub, the authors recognize the support of the other members of the Clinical Task Force of the Alzheimer's Disease Centers (ADCs), namely, John C. Morris (chair), Helena Chui, Jeffrey Cummings, Charles DeCarli, Steven Ferris, Norman Foster, Douglas Galasko, Neill Graff-Radford, and Elaine Peskind. Alzheimer Disease & Associated Disorders: April-June 2009 - Volume 23 - Issue 2 - p 102-109 doi: 10.1097/WAD.0b013e318193e376 Buy Metrics Abstract Researchers from Alzheimer's Disease Centers (ADCs) across the United States with expertise in the assessment of Spanish-speaking elderly collaborated to create the official Spanish version of measures in the Uniform Data Set of the National Institute on Aging Alzheimer's Disease Center Program. The present article describes this project, whose primary goal was to create Spanish instruments with cultural and linguistic equivalence to the English versions. The resulting Spanish versions make provisions for variations among Spanish-speaking groups in the United States of different nationalities, socio-cultural, linguistic, and educational backgrounds. A consensus-based translation and adaptation approach was used, and guiding principles and specific components of this process are summarized. The Spanish translation and adaptation of the Uniform Data Set measures became available online to ADCs in April 2007. Its creation is important, as the resulting effort provides standardized measures for the collection of cross-sectional and longitudinal data on a large cohort of Spanish-speaking elders across the country and facilitates collaborative research among ADCs. © 2009 Lippincott Williams & Wilkins, Inc.