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Immunohistochemical Detection of the BRAF V600E-mutated Protein in Papillary Thyroid Carcinoma


The American Journal of Surgical Pathology: October 2012 - Volume 36 - Issue 10 - p 1578
doi: 10.1097/PAS.0b013e3182733d9e
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This article had a minor systematic error affecting both subgroups equally. In several patients age at time of data collection, not at surgery was used for calculations.

The mean age of all patients at time of surgery was 48.2±16.6 years (5-79), in patients with mutated BRAF 51.8±14.6 years (21-79), and 44.1±18 years (5-79) in patients without BRAF mutation (Table 1). BRAF mutation was significantly associated with higher age of patients (P=0.01, Mann Whitney U-test).1

The rest of the results and all conclusions remain unchanged.


1. Koperek O, Kornauth C, Capper D, et al. Immunohistochemical detection of the BRAF V600E-mutated protein in papillary thyroid carcinoma. Am J Surg Pathol. 2012;36:844–850
© 2012 Lippincott Williams & Wilkins, Inc.