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Single intra-articular platelet-rich plasma versus corticosteroid injections in the treatment of adhesive capsulitis of the shoulder

a cohort study

Barman, Apurba, MD1; Mukherjee, Somnath, MD2; Sahoo, Jagannatha, DNB1; Maity, Rituparna, MD3; Rao, P. Bhaskar, MD4; Sinha, Mithilesh K., MS5; Sahoo, Dibyajyoti, MD2; Tripathy, Sujit, MS6; Patro, Binod Kumar, MD7; Bag, Nerbadyswari Deep, MD8

American Journal of Physical Medicine & Rehabilitation: January 23, 2019 - Volume Publish Ahead of Print - Issue - p
doi: 10.1097/PHM.0000000000001144
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Objective To compare the effects of single intra-articular platelet-rich plasma (PRP) and corticosteroid (CS) injections in patients with adhesive capsulitis (AC) of the shoulder.

Design Patients aged 18-70 years of either sex, diagnosed with AC of shoulder, with <6 months duration were included. In IA-CS (control) group, 30 patients received single injection (4ml) of IA-CS and in IA-PRP (test) group, 30 patients received single IA-PRP injection (4ml) into the GH joint under ultrasound guidance. All patients were prospectively followed for 12 weeks.

Results 28 patients in IA-PRP group and 27 in IA-CS group finished the entire 12 week study period. At 12 weeks, decrements in VAS and total SPADI scores, in IA-PRP group were 58.4 and 55.1, compared to 48.7 and 45.8 in IA-CS group. In ROM, IA-PRP group showed significant improvement in passive abduction, internal and external rotations compared to IA-CS group (-50.4 versus -39.4), (-36.8 versus -25.8), (-35.4 versus -25.9) respectively. No major complications were observed in any patients.

Conclusions At 12 week follow up, a single dose of IA-PRP injection was found to be more effective than an IA-CS injection, in terms of improving pain, disability, and shoulder ROM in patients with AC of the shoulder.

1Department of Physical Medicine and Rehabilitation, All India Institute of Medical Sciences, Bhubaneswar, India.

2Department of Transfusion Medicine, All India Institute of Medical Sciences, Bhubaneswar, India.

3Department of Pharmacology, All India Institute of Medical Sciences, Bhubaneswar, India.

4Department of Anesthesia and Intensive Care, All India Institute of Medical Sciences, Bhubaneswar, India.

5Department of General Surgery, All India Institute of Medical Sciences, Bhubaneswar, India.

6Department of Orthopedics, All India Institute of Medical Sciences, Bhubaneswar, India.

7Department of Community & Family Medicine, All India Institute of Medical Sciences, Bhubaneswar, India.

8Department of Radiodiagnosis, All India Institute of Medical Sciences, Bhubaneswar, India.

Correspondence: Apurba Barman, M.D., Department of PM&R, All India Institute of Medical Sciences, Bhubaneswar, Patrapada, Dumuduma, Bhubaneswar, Odisha, India 751019, Contact number: +91-9438884211, email: apurvaa23@gmail.com

Authors Disclosures:

Funding / Grants: The study was supported by Institutional Intramural Research Grant, All India Institute of Medical Sciences, Bhubaneswar, India. Grant No. IMF 21/2016

In this study, there was no competing interests or financial benefits to the authors.

Details of any previous presentation of the research, manuscript, or abstract in any form: Not presented anywhere

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