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Relationship Between Body Mass Index and Rehabilitation Outcomes in Subacute Stroke with Dysphagia

Morone, Giovanni, MD, PhD1; Iosa, Marco, PhD1; Paolucci, Teresa, MD, PhD2; Muzzioli, Luca, MS1; Paolucci, Stefano, MD1

American Journal of Physical Medicine & Rehabilitation: February 12, 2019 - Volume Publish Ahead of Print - Issue - p
doi: 10.1097/PHM.0000000000001159
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Objective To investigate the association between body mass index (BMI) and rehabilitation outcome in hemiparetic patients with stroke in subacute phase.

Design This was a prospective study testing the correlation between BMI and the effectiveness of rehabilitation, measured using Barthel Index (BI) scores. We enrolled patients with subacute stroke (n=664, age 68±14 years, length of hospital stay 84±34 days). We assessed the BMI and BI both at admission and discharge. The effectiveness of rehabilitation was computed as the percentage increment in BI score with respect to the maximum achievable improvement.

Results Effectiveness of rehabilitation was significantly correlated with the BMI at discharge (R=0.111, p=0.004) and percentage change in BMI (R=0.253, p<0.001), but not with BMI at admission (R=0.006, p=0.869).

Conclusions In addition to BMI value, our findings suggest that rehabilitation outcomes can be influenced by the change in BMI during rehabilitation.

1 Clinical Laboratory of Experimental Neurorehabilitation, IRCCS Santa Lucia Foundation. Via Ardeatina, 306 – 00179. Rome, Italy.

2 Complex Operative Unit in Physical Medicine and Rehabilitation, Azienda Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.

No part of the manuscript has been submitted for publication elsewhere and will not be submitted elsewhere while under consideration for this journal. None of the authors has any commercial interest to the subject of the manuscript.

Authors declare that no funding was received.

Corresponding author: Giovanni Morone, MD, PhD, Via Ardeatina 306, Rome, Italy. email: g.morone@hsantalucia.it. phone +390651501005. fax +390651501004

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