Case ReportsThe Role of FLIR ONE Thermography in Complex Regional Pain Syndrome A Case SeriesDhatt, Saroop BSc; Krauss, Emily M. MD, MSc, FRCSC; Winston, Paul MD, FRCPCAuthor Information From the University of British Columbia, Faculty of Medicine, Vancouver, British Columbia, Canada (SD); Division of Plastic Surgery, University of British Columbia, Victoria, British Columbia, Canada (EMK); and Division of Physical Medicine and Rehabilitation, Department of Medicine, University of British Columbia, Victoria, British Columbia, Canada (PW). All correspondence should be addressed to: Paul Winston, MD, FRCPC, Victoria General Hospital, 1 Hospital Way, Victoria, BC, Canada V8Z6R5. Saroop Dhatt is in training. Financial disclosure statements have been obtained, and no conflicts of interest have been reported by the authors or by any individuals in control of the content of this article. Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s Web site (www.ajpmr.com). American Journal of Physical Medicine & Rehabilitation: April 2021 - Volume 100 - Issue 4 - p e48-e51 doi: 10.1097/PHM.0000000000001522 Buy SDC Metrics Abstract Complex regional pain syndrome remains a debated syndrome characterized by symptoms and signs, including pain, sensory disturbances, thermal asymmetry, edema, and motor impairments. Thermography is a tool that assesses skin surface temperature distribution. Current literature focuses on the role of thermography for diagnostic purposes; however, its role in monitoring the response to treatment in complex regional pain syndrome is unclear. We present a case series of four patients with complex regional pain syndrome where a FLIR ONE thermal imaging camera (FLIR Systems, Inc, Wilsonville, OR) was used to assist in the diagnosis of complex regional pain syndrome, capture the effects of diagnostic nerve blocks to evaluate a peripheral nerve contribution to complex regional pain syndrome, as well as monitor and assess treatment efficacy with prednisone and surgery. Four patients were screened by clinical assessment to meet the Budapest Criteria. The thermal images revealed improvement in the temperature distribution after therapeutic intervention. We also noted temporary but immediate changes on thermal imaging with diagnostic nerve blocks. Our cases suggest that the FLIR ONE thermal imaging camera has the potential to be an accessible monitoring tool to assist in diagnosis and assess treatment efficacy in complex regional pain syndrome over time. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.