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Exercise Interventions for Individuals With Neurological Disorders

A Systematic Review of Systematic Reviews

Lai, Chien-Hung MD, PhD; Chen, Hung-Chou MD; Liou, Tsan-Hon MD, PhD; Li, Wei MD; Chen, Shih-Ching MD, PhD

American Journal of Physical Medicine & Rehabilitation: October 2019 - Volume 98 - Issue 10 - p 921–930
doi: 10.1097/PHM.0000000000001247
Literature Review
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Fall prevention requires a multifaceted approach that should include individual risk assessment and intervention strategies. Exercise interventions may mitigate most risk factors for falls (eg, balance impairment, gait impairment, and muscle weakness). Numerous systematic reviews or meta-analyses have assessed the effectiveness of exercise interventions among people with various types of neurological disorders; however, the evidence obtained has not been synthesized into an overview. Therefore, the present systematic review assessed systematic reviews of exercise intervention for fall prevention among people with neurological disorders. The research sources were the Cochrane Database of Systematic Reviews, PubMed, and Embase. Eligible studies were selected, and data were extracted independently by two reviewers. A total of 15 studies (six systematic reviews and nine meta-analyses) were included. These systematic reviews examined in this study have demonstrated that exercise interventions reduced the number, frequency, and rate of falls among people with neurological disorders, including cognitive impairment, dementia, and Parkinson disease. Furthermore, the current study presented insufficient evidence regarding the effectiveness of exercise interventions for fall prevention among people with stroke, multiple sclerosis, and diabetes mellitus with polyneuropathy. Therefore, additional investigations are necessary to evaluate the effectiveness of exercise for fall prevention among people with multiple sclerosis, stroke, and diabetes mellitus with polyneuropathy.

From the Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan (C-HL, H-CC, T-HL, S-CC); Department of Physical Medicine and Rehabilitation, Taipei Medical University Hospital, Taipei, Taiwan (C-HL, WL, S-CC); and Department of Physical Medicine and Rehabilitation, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan (H-CC, T-HL).

All correspondence should be addressed to: Shih-Ching Chen, MD, PhD, Department of Physical Medicine and Rehabilitation, Taipei Medical University Hospital, No 252, Wuxing St, Taipei City 110, Taiwan.

Financial disclosure statements have been obtained, and no conflicts of interest have been reported by the authors or by any individuals in control of the content of this article.

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Online date: June 18, 2019

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