The aim of this study was to evaluate if an early rehabilitation program for survivors of critical illness improves functional recovery, reduces length of stay, and reduces hospital costs.
This was a prospective randomized controlled trial. Fifty-three consecutive survivors of critical illness were included in the study. After discharge from the intensive care unit, the intervention group received an early rehabilitation program, and the standard-care group received physical therapy as ordered by the primary care team. Length of stay at the general ward after transfer from the intensive care unit was recorded. In addition, Early Rehabilitation Barthel Index, visual analog scale for pain, 3-minute walk test, Beck Depression Inventory, State-Trait Anxiety Inventory, and Medical Research Council scale were used.
In the per-protocol analysis, length of stay at the general ward was a median 14 days (interquartile range [IQR], 12–20 days) in the early rehabilitation and 21 days [IQR, 13–34 days) in the standard-care group. This significant result could not be confirmed by the intention-to-treat analysis (16 days [IQR, 13–23 days] vs. 21 days [IQR, 13–34 days]). Secondary outcomes were similar between the groups. Hospital costs were lower in the intervention group. No adverse effects were detected.
An early rehabilitation program in survivors of critical illness led to an earlier discharge from the hospital, improved functional recovery, and was also cost-effective and safe.
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From the Department of Physical Medicine and Rehabilitation, Medical University of Vienna, General Hospital Vienna (WG, KP, CH, TP-S); Center for Medical Statistics, Informatics, and Intelligent Systems, Section for Medical Statistics, Medical University of Vienna (IS); Department of Anaesthesia and Intensive Care, Medical University of Vienna, General Hospital Vienna (JMH); and Department of Physical Medicine and Rehabilitation, Danube Hospital Vienna, Vienna Hospital Association (TP-S), Vienna, Austria.
All correspondence and requests for reprints should be addressed to: Karin Pieber, MD, Department of Physical Medicine and Rehabilitation, Medical University of Vienna, General Hospital Vienna, Waehringer Guertel 18-20, Vienna 1090, Austria.
This study was supported by funds of the Oesterreichische Nationalbank (Anniversary Fund, project no. 12751) awarded to T.P.-S. The funding source had no role in the study concept, design, data collection, data analysis, data interpretation or the writing of the report. The researchers I.S., C.H., Matthias Lenz, and Bryon Hofbauer have received honoraria from this grant. For the remaining authors, none were declared.
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