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Cognitive Dysfunction Among Cancer Survivors

Asher, Arash MD

American Journal of Physical Medicine & Rehabilitation: May 2011 - Volume 90 - Issue 5 - p S16-S26
doi: 10.1097/PHM.0b013e31820be463
Invited Reviews

Cognitive dysfunction among cancer survivors, commonly referred to as "chemobrain," has gained increased attention in the last decade. Cognitive dysfunction is now well recognized among patients with non-central nervous system cancers. It may be a consequence of the cancer, its treatment, or both. Other common problems among cancer survivors, such as insomnia, pain, depression, and fatigue, may play a role in cognitive performance. Three options to assess cognitive function at present include neuropsychologic testing, functional neuroimaging studies, and subjective evaluations, although no "gold standard" currently exists. Treatment options for survivors with cognitive problems are limited because research in this arena is in its infancy.

From the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California.

All correspondence and requests for reprints should be addressed to: Arash Asher, MD, Cancer Survivorship and Rehabilitation, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, 8700 Beverly Blvd, C-2000, Los Angeles, CA 90048.

Financial disclosure statements have been obtained, and no conflicts of interest have been reported by the authors or by any individuals in control of the content of this article.

© 2011 Lippincott Williams & Wilkins, Inc.