Blood Volume and Hemoglobin After Spinal Cord InjuryHoutman, Sibrand MSc; Oeseburg, Berend PhD, MD; Hopman, Maria T. E. PhD, MDAmerican Journal of Physical Medicine & Rehabilitation: May-June 2000 - Volume 79 - Issue 3 - p 260-265 CME Article: Spinal Cord Injury Buy SDC Abstract Author InformationAuthors Objective: The main purpose of this study was to investigate the difference in total blood volume and hemoglobin mass between spinal cord-injured and able-bodied individuals. Design: Total blood volumes of 13 able-bodied and 10 spinal cord-injured individuals (lesion >T4) were determined using the carbon monoxide method. The reproducibility of the total blood volume determination in our setting and the effect of increased physical activity were assessed. Results: Comparison of groups showed a significantly higher hemoglobin mass in able-bodied compared with spinal cord-injured individuals. The total blood volume expressed per kilogram of body mass in able-bodied individuals was significantly greater than in spinal cord-injured individuals. Conclusions: These results suggest that total blood volume and hemoglobin mass are decreased in spinal cord-injured individuals with a lesion above T4, which may be related to their inactive lifestyle, because total blood volume increased with increased physical activity in these subjects. From the Department of Physiology, University of Nijmegen, Nijmegen, The Netherlands. Reprints: All correspondence should be addressed to Sibrand Houtman, MSc, Department of Physiology, University of Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands. Disclosures: Presented at the annual meeting of the ACSM, June 1999. 2000 Series · Number 8 © 2000 Lippincott Williams & Wilkins, Inc.