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1.5 CE Test Hours

Hematologic Childhood Cancers

An Evidence-Based Review

Contrada, Emily

AJN, American Journal of Nursing: December 2019 - Volume 119 - Issue 12 - p 45
doi: 10.1097/


  • Read the article. Take the test for this CE activity online at
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  • Registration deadline is December 3, 2021.


LPD will award 1.5 contact hours for this continuing nursing education (CNE) activity. LPD is accredited as a provider of CNE by the American Nurses Credentialing Center's Commission on Accreditation.

This activity is also provider approved by the California Board of Registered Nursing, Provider Number CEP 11749 for 1.5 contact hours. LPD is also an approved provider of CNE by the District of Columbia, Georgia, and Florida #50-1223. Your certificate is valid in all states.


The registration fee for this test is $17.95.

Hematologic Childhood Cancers: An Evidence-Based Review


To provide information about the therapies used to treat hematologic cancers and the nursing care of the child and family.


After completing this continuing education activity, you should be able to

  • compare and contrast the characteristics and manifestations of hematologic childhood cancers.
  • summarize appropriate assessment and interventions for pediatric patients with hematologic cancers.
  1. To reduce the adverse effects of treatment, combination chemotherapy uses antineoplastic agents
    1. administered via different routes.
    2. with dissimilar toxicity profiles.
    3. with similar mechanisms of action.
  2. Negatively charged particles delivered by radiation therapy that are absorbed in tissue at a limited depth are
    1. protons.
    2. photons.
    3. electrons.
  3. Unlike traditional chemotherapy drugs, targeted cancer therapies
    1. kill all rapidly dividing cells.
    2. seek out genetic markers that identify cancer cells.
    3. induce immunosuppression to reduce proliferation.
  4. Autologous stem cells are
    1. reinfused after the patient undergoes a regimen of high-dose chemotherapy.
    2. harvested from the patient before chemotherapy begins.
    3. collected from healthy related or unrelated donors.
  5. Which of the following is an initial manifestation in more than one-third of children who have leukemia?
    1. fatigue
    2. hypothermia
    3. abdominal pain
  6. Acute lymphoblastic leukemia (ALL) is diagnosed when bone marrow morphology reveals more than which of the following percentages of blast cells?
    1. 15%
    2. 20%
    3. 25%
  7. Which of the following features of ALL requires more intensive combination chemotherapy regimens?
    1. an age of 4 to 8 years
    2. the involvement of sanctuary sites
    3. an initial white blood cell count of 40,000/microliters or less
  8. During which phase of pediatric ALL therapy are several different chemotherapeutic agents administered, with the goal of achieving complete remission?
    1. induction
    2. consolidation
    3. maintenance
  9. Pediatric patients who have acute promyelocytic leukemia commonly present with
    1. systolic hypertension.
    2. intractable headache.
    3. severe bleeding.
  10. For postremission consolidation in childhood acute myelogenous leukemia, which of the following therapies has shown no benefit?
    1. allogeneic hematopoietic stem cell transplantation (HSCT)
    2. intrathecal chemotherapy
    3. autologous HSCT
  11. With Hodgkin lymphoma, an example of a B symptom is
    1. drenching night sweats.
    2. any spike in temperature above 99.5°F (37.5°C).
    3. unexplained weight loss of at least 5% of body weight over a 6-month period.
  12. Which of the following treatments for Hodgkin lymphoma is avoided when possible owing to risks of cardiovascular disease and secondary cancers?
    1. autologous HSCT
    2. radiation therapy
    3. monoclonal antibodies
  13. In non-Hodgkin lymphoma (NHL), the presence of primary intrathoracic tumors or extensive abdominal disease results in classification of the disease as stage
    1. II.
    2. III.
    3. IV.
  14. The mainstay of treatment in NHL is
    1. surgery.
    2. radiation therapy.
    3. systemic, multiagent chemotherapy.
  15. To reduce the risk of central line–associated bloodstream infections, which of the following is recommended as a part of central venous catheter care?
    1. chlorhexidine gluconate
    2. povidone-iodine
    3. hydrogen peroxide
  16. According to Tucquet and Leung, children with cancer reported significantly lower pain scores and anxiety levels when provided with which of the following before, during, and after a painful procedure?
    1. audiobooks
    2. music therapy
    3. medical play therapy
  17. Parents should be advised that which of the following should prompt a call to the child's oncologist?
    1. dizziness
    2. fatigue
    3. nausea
  18. When a child is neutropenic, which of the following is an oncologic emergency warranting immediate intervention?
    1. limb pain
    2. weakness
    3. fever
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