1.5 CE Test Hours Type 2 Diabetes A Pharmacologic UpdateContrada, EmilyAJN The American Journal of Nursing: March 2019 - Volume 119 - Issue 3 - p 42 doi: 10.1097/01.NAJ.0000554009.84637.8a Feature Articles Free CE Article OutlineOutline Article MetricsMetrics TEST INSTRUCTIONS PROVIDER ACCREDITATION PAYMENT Type 2 Diabetes: A Pharmacologic Update GENERAL PURPOSE: LEARNING OBJECTIVES/OUTCOMES: Back to Top | Article Outline TEST INSTRUCTIONS Read the article. Take the test for this CE activity online at www.nursingcenter.com/ce/ajn. You'll need to create and log in to your personal CE Planner account before taking online tests. Your planner will keep track of all your Lippincott Professional Development (LPD) online CE activities for you. There is only one correct answer for each question. The passing score for this test is 13 correct answers. If you pass, you can print your certificate of earned contact hours and the answer key. If you fail, you have the option of taking the test again at no additional cost. For questions, contact LPD: 1-800-787-8985. Registration deadline is March 5, 2021. Back to Top | Article Outline PROVIDER ACCREDITATION LPD will award 1.5 contact hours for this continuing nursing education (CNE) activity. LPD is accredited as a provider of CNE by the American Nurses Credentialing Center's Commission on Accreditation. This activity is also provider approved by the California Board of Registered Nursing, Provider Number CEP 11749 for 1.5 contact hours. LPD is also an approved provider of CNE by the District of Columbia, Georgia, and Florida #50-1223. Your certificate is valid in all states. Back to Top | Article Outline PAYMENT The registration fee for this test is $17.95. Back to Top | Article Outline Type 2 Diabetes: A Pharmacologic Update GENERAL PURPOSE: To provide information about established as well as more recently introduced type 2 diabetes treatments and the nursing implications for patient teaching and monitoring for adverse effects. Back to Top | Article Outline LEARNING OBJECTIVES/OUTCOMES: After completing this continuing education activity, you should be able to outline indications and contraindications for the drugs discussed in this article. identify adverse effects related to these drugs. summarize key points for patient teaching about these drugs. For treating type 2 diabetes mellitus, metformin is one of the more expensive antidiabetic drugs available. the first-line drug when nonpharmacologic therapy is not effective. known to cause significant weight gain in most patients who use it. The most serious adverse effect associated with metformin is osteoporosis. renal toxicity. lactic acidosis. Metformin is associated with deficiency of which of the following vitamins? B12 D K Compared with metformin, sulfonylureas have a lower risk of weight gain. higher risk of hypoglycemia. lower risk of cardiovascular mortality. The second-generation sulfonylurea that patients should take on an empty stomach 30 minutes before a meal is glimepiride. glyburide. glipizide. Meglitinides act by inhibiting gluconeogenesis and glycogenolysis to reduce hepatic glucose output. altering the ATP-sensitive potassium channel of the pancreatic beta cells. impeding the conversion of oligosaccharides to monosaccharides. Of the following, the most commonly reported adverse effect of meglitinide use is hypoglycemia. nasopharyngitis. abdominal bloating. Thiazolidinediones act by filtering glucose reabsorption in the proximal tubules of the kidney. impeding the conversion of oligosaccharides to monosaccharides. directly increasing insulin sensitivity in muscle, fat, and liver tissues. A contraindication for thiazolidinedione use is osteopenia. renal disease. bowel disorders. Taking thiazolidinediones may increase the risk of bleeding. pregnancy. thyroid tumors. A contraindication for taking α-glucosidase inhibitors is osteopenia. renal disease. bowel disorders. There have been reports that use of dipeptidyl peptidase 4 (DPP-4) inhibitors may be associated with amputation. acute pancreatitis. myocardial infarction. Patients should take DPP-4 inhibitors 3 times a day with a meal. on arising and again at bedtime. once daily, with or without meals. Which glucagon-like peptide 1 (GLP-1) receptor agonist is approved by the U.S. Food and Drug Administration for treating obesity? exenatide liraglutide albiglutide Which GLP-1 receptor agonist is a long-acting agent administered once weekly? exenatide liraglutide albiglutide Clinical trials with liraglutide have reported thyroid neoplasms. mycotic infections. decreased calcitonin levels. Adverse reactions to sodium–glucose cotransporter 2 inhibitors include hypotension. thrombocytopenia. urinary tract infections. Canagliflozin may increase the risk of fracture. hypokalemia. tendon rupture. Adverse reactions to pramlintide include increased appetite. vomiting. myalgia. Pramlintide should be injected into the thigh or abdomen. buttocks. upper arm. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.