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1.5 CE Test Hours

A Review of Current Practice in Transfusion Therapy

Contrada, Emily

AJN The American Journal of Nursing: May 2018 - Volume 118 - Issue 5 - p 45,46
doi: 10.1097/01.NAJ.0000532809.89337.8a
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A Review of Current Practice in Transfusion Therapy


To provide information about commonly transfused blood products.

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After completing this educational activity, you should be able to

  • identify commonly transfused blood products.
  • outline potential complications of blood transfusions and their signs and symptoms.
  • list current recommendations for transfusion therapy widely supported by the medical and nursing literature.
  1. Each year in the United States, about how many million patients receive transfusions of blood components?
    1. 2.3
    2. 4.5
    3. 6.7
  2. Patients with acute burn injuries may require up to how many units of platelets?
    1. 20
    2. 35
    3. 50
  3. Which of the following is the most commonly transfused of all blood products?
    1. platelets
    2. cryoprecipitate
    3. packed red blood cells
  4. Fresh frozen plasma is transfused primarily to
    1. treat coagulation deficiencies.
    2. expand circulating volume.
    3. increase oxygen-carrying capacity.
  5. Thawed plasma must be discarded if it is not transfused within how many hours of preparation?
    1. 12
    2. 24
    3. 36
  6. Cryoprecipitate is used to treat deficiency of which of the following?
    1. folic acid
    2. erythropoietin
    3. fibrinogen
  7. People with type O blood express which of the following antigens on their red blood cells?
    1. A but not B
    2. neither A nor B
    3. both A and B
  8. An example of a delayed transfusion reaction is
    1. posttransfusion purpura.
    2. transfusion-related acute lung injury (TRALI).
    3. a febrile nonhemolytic transfusion reaction.
  9. A manifestation of an acute hemolytic transfusion reaction is
    1. hypothermia.
    2. bradycardia.
    3. chest pain.
  10. In response to any acute transfusion reaction, which action should nurses take first?
    1. Initiate a normal saline infusion.
    2. Stop the blood product transfusion.
    3. Assess the patient for coagulopathy.
  11. A clinical manifestation of a severe systemic allergic reaction is
    1. abdominal pain.
    2. hypertension.
    3. chills.
  12. Which of the following medications treats an anaphylactic transfusion reaction?
    1. atropine
    2. dopamine
    3. epinephrine
  13. Which of the following medications should patients who require transfusion therapy and are at risk for transfusion-associated circulatory overload receive?
    1. diuretics
    2. anticoagulants
    3. antihistamines
  14. Patients who develop TRALI have an acute onset of respiratory distress and pulmonary edema within how many hours of transfusion?
    1. 3
    2. 6
    3. 9
  15. With TRALI, immune mediators may produce
    1. angioedema.
    2. nausea and vomiting.
    3. blood pressure instability.
  16. Treatment for TRALI calls for aggressive respiratory support, possibly along with
    1. plasmapheresis.
    2. fluid restriction.
    3. immunoglobulins.
  17. A clinical manifestation of transfusion-associated graft versus host disease (TA-GVHD) is
    1. diarrhea.
    2. headache.
    3. hypothermia.
  18. Prior to transfusion, which of the following is a preventive strategy for TA-GVHD?
    1. minimizing colloid use
    2. assessing fluid-volume status
    3. irradiating donor lymphocytes
  19. Several of the additive solutions that preserve and store blood products put patients at risk for various imbalances, including
    1. metabolic acidosis.
    2. hyperglycemia.
    3. respiratory alkalosis.
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