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Risk of Rare, Serious Genital Infection from some Diabetes Drugs

Aschenbrenner, Diane S. MS, RN

AJN The American Journal of Nursing: December 2018 - Volume 118 - Issue 12 - p 23
doi: 10.1097/01.NAJ.0000549687.43759.a5
Drug Watch
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  • Sodium–glucose cotransporter-2 (SGLT2) inhibitors, used to treat type 2 diabetes, now carry a warning regarding the risk of necrotizing fasciitis of the perineum.
  • NPs should assess for this rare genital infection if a patient taking an SGLT2 inhibitor presents with redness, swelling, and pain in the genitals or in the area from the genitals to the rectum, and has a fever above 100.4°F or general malaise.

Diane S. Aschenbrenner is an assistant professor at Notre Dame of Maryland University in Baltimore. She also coordinates Drug Watch: daschenbrenner@ndm.edu.

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