Labeling Changes Promoting Safe Use of Long-Acting OpioidsAschenbrenner, Diane S. MS, RNAJN The American Journal of Nursing: January 2014 - Volume 114 - Issue 1 - p 24,25 doi: 10.1097/01.NAJ.0000441788.62785.29 Drug Watch Abstract Author Information The labeling of extended-release and long-acting opioid analgesics has been revised to warn practitioners that the drugs have been associated with misuse, abuse, life-threatening respiratory depression, accidental exposure, neonatal opioid withdrawal syndrome, and (with some drugs) serious drug interactions with alcohol. The labeling will also state that long-acting opioids should only be used if other pain relief methods aren't effective. Diane S. Aschenbrenner recently retired as course coordinator for undergraduate pharmacology at Johns Hopkins University School of Nursing in Baltimore, MD. She also coordinates Drug Watch: email@example.com. © 2014 Lippincott Williams & Wilkins. All rights reserved.