New Warning for TramadolAschenbrenner, Diane S. MS, APRN-BCAJN The American Journal of Nursing: September 2010 - Volume 110 - Issue 9 - p 28 doi: 10.1097/01.NAJ.0000388259.18933.c4 Drug Watch Abstract Author Information Tramadol (Ultram) and tramadol with acetaminophen (Ultracet) may increase the risk of suicide in those with a history of suicidal ideation, who abuse alcohol or other drugs, or who take tranquilizers or antidepressants. Overdosage of tramadol can cause severe CNS depression and death. Diane S. Aschenbrenner is the course coordinator for undergraduate pharmacology at Johns Hopkins University School of Nursing in Baltimore, MD. She also coordinates Drug Watch: firstname.lastname@example.org. © 2010 Lippincott Williams & Wilkins, Inc.