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Pharmacogenomics: Personalizing Drug Therapy

Kudzma, Elizabeth C. DNSc, MPH, WHNP-BC; Carey, Eileen T. BS, RN

AJN The American Journal of Nursing: October 2009 - Volume 109 - Issue 10 - p 50-57
doi: 10.1097/01.NAJ.0000361493.75589.06
Feature Articles

Pharmacogenomics is a rapidly growing field of research into the ways in which genetic variation affects drug response. Its objective is to develop precisely targeted, optimal drug therapy. One area of pharmacogenomics focuses on identifying genetic markers for differences in the way people metabolize drugs; another concentrates on developing genetic tests that predict how specific patients will respond to agents such as statins or cancer therapies. Nurses are now called upon to interpret such information or services in order to provide appropriate patient teaching regarding drug selection.

This rapidly growing field is generating a wealth of information that nurses can put into practice at the bedside.

Elizabeth C. Kudzma is a professor in the Division of Nursing at Curry College, Milton, MA, and Eileen T. Carey is a staff nurse at Sturdy Memorial Hospital, Attleborough, MA.

Contact author: Elizabeth C. Kudzma,

The authors of this article have no significant ties, financial or otherwise, to any company that might have an interest in the publication of this educational activity.

© 2009 Lippincott Williams & Wilkins, Inc.