ArticleElectronic Family History Screening Tool for Detection of Inherited Cancer Risk A Prospective Pilot StudyLe, Amy MD1; Valice, Emily MPH2; Kobelka, Christine MSc3; Janes, Kristen BS4; Hoodfar, Elizabeth MSc3; Powell, C. Bethan MD2,5 Author Information 1Department of Obstetrics and Gynecology, Kaiser Permanente San Francisco Medical Center, San Francisco, CA 2Division of Research, Kaiser Permanente Northern California, Oakland, CA 3Department of Genetics, Kaiser Permanente San Francisco Medical Center, San Francisco, CA 4National Quality, Kaiser Permanente, Oakland, CA 5Kaiser Permanente Northern California Gynecologic Cancer Program, San Francisco, CA Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s Web site (www.ajmqonline.com). Corresponding Author: C. Bethan Powell, MD, Kaiser Permanente Northern California Gynecologic Cancer Program, 2238 Geary Blvd, San Francisco, CA 94115. Email: [email protected] Online date: June 10, 2021 American Journal of Medical Quality: November/December 2021 - Volume 36 - Issue 6 - p 415-421 doi: 10.1097/01.JMQ.0000735504.65700.25 Buy SDC Metrics Abstract Family history screening to identify individuals at increased risk for hereditary cancers could be a powerful strategy to prevent cancer but is used inconsistently in primary care. The objective was to improve identification of women with at-risk family histories using a point-of-care family history screening tool administered on an electronic tablet device during well-woman appointments. A total of 288 women were invited to participate and 136 women (47.2%) completed the electronic family history screening tool. Significantly more women were identified and referred to the genetics department with the electronic family history screening tool than the standard-of-care paper questionnaire (11.8% versus 0.8%, P < 0.001). There were no statistically significant differences in the proportion of referred women who were evaluated by the genetic counselors, and no pathogenic variants were found with either family history screening method. Implementing innovative self-reporting tools may improve inherited cancer risk detection. Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved.