Predictors of Satisfaction With Life Among Adult Patients With Established Crohn’s Disease: 1646 : Official journal of the American College of Gastroenterology | ACG

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Predictors of Satisfaction With Life Among Adult Patients With Established Crohn’s Disease


Sarid, Orly PhD1; Slonim-Navo, Vered PhD1; Friger, Michael PhD2; Vardi, Hillel MS2; Schwartz, Doron MD3; Munteau, Daniela MD3; Dizengof, Vitaly MD3; Moshkelo, Alex MD3; Rozental, Alex MD3; Yaakov, Gil Ben MD3; Krugliak, Pavel MD3; Freha, Naim Abu MD3; Eidelman, Leslie MD3; Gaspar, Nava MD3; Fich, Alex MD3; Greenberg, Dan PhD4; Odes, Shmuel MD5

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American Journal of Gastroenterology 109():p S488, October 2014.
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Introduction: From studies of the psychopathology of patients with Crohn’s disease (CD) it is postulated that the degree of satisfaction with life is a personality resource that impacts on their ability to cope with the adverse effects of the disease. Yet, the demographic, psychological and family support factors that predict the protective salutary effects of this resource among CD patients are incompletely understood.

Methods: Consecutive CD patients undergoing clinical follow-up at the IBD Clinic completed the following socio-psychological questionnaires: McMaster family assessment device (FAD, assesses respondents’ perceptions of functioning and communication in their family, Epstein et al. 1983), satisfaction with life scale (SWLS, measures respondents’ subjective well-being, Diener et al. 1985) and brief symptom inventory (BSI, defines psychological symptoms, Deragotis & Melisaratos 1983) in addition to demographiceconomic documentation and IBDQ. Pooled demographic variables, negative psychological well-being variables, familial functioning variables, and the Harvey-Bradshaw index (HBI) of disease severity and IBDQ were included a linear regression model, with SWLS as the dependent variable. The data are presented as mean ± standard deviation.

Results: There were 192 patients: 81 men (age 36.8±14.5 years, disease duration 11.4±8.6 years, education 13.7±2.7 years, HBI 7.6±4.9, IBDQ 48.1±15.4) and 111 women (41.4±15.6*, 14.0±9.3*, 14.2±2.8, 8.4±4.8, 47.3±13.3; *p <0.05 vs. men). The mean scores of FAD, BSI and SWLS were as follows: men: 1.79±0.59, 0.95±0.92 and 21.6±7.9, and women: 1.66±0.55, 0.89±0.82 and 23.3±7.0 (p=ns vs. men). In an overall model of the cohort, three variables were found to be significant predictors for satisfaction with life among CD patients. The percent of explained variance of the model is 50.9%, adjusted R square =0.501 (Table). Additional significant components of BSI impacting SWLS included phobic anxiety and somatization. Severity of disease and age at onset of disease did not impact on satisfaction with life. BSI depression was correlated with IBDQ (r=-0.631).

Conclusion: Satisfaction with life was contingent upon higher economic status, absence of depression, and good family functioning. Physicians should examine Crohn’s disease patients for signs of depression, and explore family relationships in order to help their patients cope with the disease. Supported by a generous grant from the Leona M. and Harry B. Helmsley Charitable Trust.

Table 1:
Regression analysis
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