Barrett's Esophagus Eradication With Radiofrequency Ablation in Patients With Altered Anatomy

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Purpose: Radiofrequency ablation (RFA) is an effective and proven therapeutic treatment modality for Barrett's esophagus (BE), with complete eradication rates upwards of 80%. Despite high rates of eradication, some patients don't respond to RFA. We examined a series of five patients with altered anatomy who underwent RFA treatment for Barrett's Esopahgus.

Cases: We describe a series of 5 patients with altered anatomy, who underwent RFA treatment for dysplastic BE, with high rates of successful eradication. Three patients had prior Ivor-Lewis esophagectomy, and 2 patients had prior gastric-bypass. Of the three who underwent Ivor-Lewis, two had successful eradication (66%), and of the two who had prior gastric bypass (both roux-en-Y), both had successful eradication (100%). Of the five patients, 80% had complete eradication of dysplastic Barrett's Esophagus. Additionally, of the five patients, the average length of Barrett's Esophagus segment was This case series is important in demonstrating that patients with altered anatomy can still be successfully treated with RFA for dysplastic Barrett's Esophagus. More research is needed to determine if certain types of altered anatomy are more likely to have successful eradication of dysplastic Barrett's Esophagus.