Supplement Abstracts Submitted for the 70th Annual Scientific Meeting of the American College of Gastroenterology: STOMACH
Purpose: To examine the prevalence of H. Pylori (HP) in gastric carcinoma (GC) in our community practice.
Methods: We retrospectively reviewed 49 patients found to have a diagnosis of GC between 1/90–12/04 in our private practice in Orlando, Fl. All tumors were contained within the stomach, without extension into the esophagus. Endoscopic biopsies and surgical pathology specimens were examined for HP presence.
Results: Of 49 patients with GC, 6/49 (12%) were HP positive. 50% were female, 50% male, mean age 63 years. 74% were caucasion, 76% (37/49) had adenocarcinoma, (13/37 were signet ring type), 16% (8/49) had lymphoma, and one person each had sarcoma, malignant carcinoid, melenoma and leiomyosarcoma. 39% were located in the cardia, 20% in the body of the stomach and 41% in the antrum. Mean size of GC was 5 cm, the median was 3 cm. The most common clinical signs and symptoms were epigastric pain, anemia, weight loss and heartburn.
- Only 12% of patients had demonstrable HP at the time of endoscopic diagnosis of GC or surgical resection.
- The prevalence of GC was almost twice as high between 1990–1995, as it was between 1995–2005.
- Country of origen (for those born outside the United States) did not predict HP presence.
- Further community studies in the United States would help to assess the distribution of HP related GC geographically, enabling us to compare prevalence data with other countries and within our own diverse country.