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Considering the Supraorganism

Harnessing the Gut Microbiome for Cancer Prevention, Detection, and Treatment

Hollister, Emily B. PhD

American Journal of Gastroenterology: July 2019 - Volume 114 - Issue 7 - p 1030–1031
doi: 10.14309/ajg.0000000000000180

Although causal relationships between specific microbes and cancer are well recognized, a growing body of evidence suggests that the broader community of gut microbes may influence cancer risk, provide diagnostic insight, shape clinical course, and impact treatment success in the gastrointestinal tract and beyond. In this issue, Murphy et al. reviewed evidence for the role of the microbiome in clinical oncology. Given that the gut microbiome may be modified by treatments ranging from diet and live biotherapeutics to microbial transplantation, microbiome-directed therapies hold tremendous promise for personalized therapies and improved treatment outcomes.

Diversigen, Inc, Houston, Texas, USA.

Correspondence: Emily B. Hollister, PhD. E-mail:

Received January 15, 2019

Accepted January 25, 2019

© The American College of Gastroenterology 2019. All Rights Reserved.
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