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Fecal Microbiota Transplant for Clostridium difficile Colitis–Induced Toxic Megacolon

Costello, S P MD, FRACP1; Chung, A MD, BMedSci, FRACP2; Andrews, J M MD, FRACP, PhD, AGAF3,4; Fraser, R J MD, FRACP, PhD2,5

American Journal of Gastroenterology: May 2015 - Volume 110 - Issue 5 - p 775–777
doi: 10.1038/ajg.2015.70

1Department of Gastroenterology, The Queen Elizabeth Hospital, Adelaide, South Australia, Australia

2Department of Gastroenterology and Hepatology, Flinders Medical Centre, Adelaide, South Australia, Australia

3Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, Adelaide, South Australia, Australia

4University of Adelaide School of Medicine, Adelaide, South Australia, Australia

5School of Medicine, Flinders University of South Australia, Bedford Park, South Australia, Australia

Correspondence: Sam P. Costello, MD, FRACP, Department of Gastroenterology, The Queen Elizabeth Hospital, 28 Woodville Road, Woodville, Adelaide, South Australia 5011, Australia. E-mail:

Guarantor of the article: Professor RJ Fraser, MD,FRACP,PhD.

Specific author contributions: Dr SP Costello established the FMT service and stool bank in South Australia and provided the stool and technical instruction on the fecal transplant procedure. Dr Costello is the author of the letter. Dr A Chung performed the push enteroscopy that delivered the fecal transplant in the jejunum. Dr Chung edited the letter. Professor JM Andrews helped establish the fecal microbiota transplant service and edited the letter. Professor RJ Fraser was clinically responsible for the patient and the decision to proceed with fecal microbiota transplant. He performed the final edit of the letter and is the guarantor.

Financial support: Fecal microbiota transplant service funded by the Department of Health in South Australia.

Potential competing interests: None.

© The American College of Gastroenterology 2015. All Rights Reserved.
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