Continuing Medical Education: November 2012American Journal of Gastroenterology: November 2012 - Volume 107 - Issue 11 - p 1713 doi: 10.1038/ajg.2012.357 ORIGINAL CONTRIBUTIONS: FUNCTIONAL GI DISORDERS Buy Author InformationAuthors Article MetricsMetrics A 12-Week, Randomized, Controlled Trial With a 4-Week Randomized Withdrawal Period to Evaluate the Efficacy and Safety of Linaclotide in Irritable Bowel Syndrome With Constipation The American College of Gastroenterology is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The American College of Gastroenterology designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. © The American College of Gastroenterology 2012. All Rights Reserved.