REVIEW ARTICLE: REVIEW ARTICLEWhen to Stop Surveillance: Pancreatic CystsPetrov, Maxim S. MD, MPH, PhD1 Author Information 1School of Medicine, University of Auckland, Auckland, New Zealand. Correspondence: Maxim S. Petrov, MD, MPH, PhD. E-mail: [email protected]. The American Journal of Gastroenterology 118(3):p 440-442, March 2023. | DOI: 10.14309/ajg.0000000000002178 Buy Metrics Abstract Surveillance of mucinous pancreatic cysts is a key to reducing pancreatic cancer risk and detecting malignancy early. However, while the management of cysts with high-risk and worrisome features is fairly straightforward, surveillance of patients with low-risk branch-duct intraductal papillary mucinous neoplasms has long presented gastroenterologists with the challenging question of discontinuation of surveillance. Up-to-date evidence supports the cessation of follow-up in these patients depending on both interval stability of the cyst and cyst size. Based on these criteria, discontinuation of surveillance at either 5 years or 10 years is recommended. Oversurveillance of patients with pancreatic cysts in the absence of high-risk and worrisome features is discouraged. © 2023 by The American College of Gastroenterology